Genzyme and Isis Pharmaceuticals, Inc. announced the finalization of the license and collaboration agreement for mipomersen. The collaboration provides Genzyme with exclusive worldwide rights to mipomersen, a novel lipid-lowering drug discovered and developed by Isis that is in phase 3 clinical development. During the second half of this year, enrollment is expected to be completed in a pivotal study of mipomersen in homozygous familial hypercholesterolemia, and a new trial in apheresis-eligible patients is expected to begin. More›

Genzyme announced that it has submitted marketing applications in both the United States and the European Union for Mozobil™ (plerixafor), a product candidate intended to enhance mobilization of hematopoietic stem cells for collection and subsequent autologous transplantation in patients with lymphoma and multiple myeloma. More›

Genzyme reported preliminary data today from a fully-enrolled pivotal, phase 2 study examining the safety and effectiveness of Clolar® (clofarabine) as a single agent in previously untreated, older adult patients with acute myelogenous leukemia (AML) who are unlikely to benefit from conventional “7+3” anthracycline plus cytarabine-based induction chemotherapy. More›