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Genzyme 2004 Annual Report
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Table of Contents
2004 - A Transforming Year
Financial Highlights
Letter To Shareholders
A Future of Hope
Building a Sustainable Future
Focused Medical Areas
Genetic Diseases
Growth in our LSD Franchise
Building Sustainable Health
Renal Disease
Orthopaedics
Oncology
Transplant / Immune Diseases
Genetics / Diagnostics
A Future of Innovation
A Future of Commitment
A Future of Growth
Genetic Diseases
Genzyme's patient focus led us to pioneer therapeutic treatments for rare genetic diseases known as lysosomal storage disorders (LSDs). We now have three marketed LSD products, and a fourth has entered the regulatory approval process. Our continued success is based on our ability to meet medical needs and our global commitment to patient care.

PhotoDiagnosed with Fabry disease
Name Tag

Two-year-old Yuua has been diagnosed with Fabry disease, but his twin brother, Toshia, does not have this condition. Their mother and grandmother have also been diagnosed, and the grandmother has begun Fabrazyme therapy. Fabrazyme was approved in Japan in 2004.