To ensure our long-term growth, we pursue developments globally, as our new research center in the
United Kingdom and our worldwide cell therapy joint venture demonstrate. We are also building the
capacity and security of our supply chain by more fully globalizing our core competency in
manufacturing. We have now created clinical and regulatory affairs hubs in the United Kingdom, the
Netherlands and Japan. As 10 new countries have joined the European Union, we have established
offices in four of the key cities, ready to work with governments as they increase economic support
for improving health-care systems. We engage in such work around the world to bring our products to
more patients. Across all our product lines, we are leveraging our global technology,
manufacturing, clinical and regulatory, and sales and marketing infrastructures.